- - disconnect all MIDI cables from your synth
- start MIDI-OX and switch on both input and output monitoring in MIDI-OX (make sure in 'Options/MIDI devices' that the appropriate ports are swithced on so that you can monitor them), both input and output displays should be quiet, no data to display
- plug the interface's MIDI IN cable into the MIDI THRU of your synth - nothing should happen
- plug the MIDI OUT cable of your interface into the MIDI IN of the synth, still, nothing should happen
- activate 'play notes from your computer keyboard' (from the menu, toolbar or 'KYB' in the status bar of the MIDI-OX window - still, nothing should happen
- press one of the computer keyboard's keys, say 'X' or another from the bottom row
If you get data stream on your input monitor (or both input and output) before pressing anything on the computer keyboard then you have a problem with your MIDI configuration, because MIDI THRU cannot transmit without MIDI IN receiving data. It might be that some other program is transmitting in the background, a faulty MIDI interface (unlikely) or improperly connected cable spaghetti if you're unsing a complex MIDI setup and/or MIDI junction boxes.
The fact that your computer freezes when connecting the loopback indicates to me that there's someting wrong with your MIDI configuration, less likely with the MIDI hardware (but still, possible). Hope the above helps to test/troubleshoot your interface and configuration.