I have a Yamaha UX16 midi-usb interface with the newest drivers from Yamaha, so that shouldn't be an issue.
Thanks a lot!

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What I meant to say is that a regular type-B to type-A USB cable hooked up from the back of your M50 (USB port) to a USB port on your computer can do the same. If you still prefer to use the Yamaha cable, that should work as well.But doesn't the midi interface allow the midi signal to enter the computer?